Streets of Rage (1 and 2) was an awesome game. Perhaps the best scrolling beat 'em up ever. I remember playing at my friend's house at lunch having a blast with it. I also remember wishing that the Turbo would release a game like this.
I will tell you one thing, and I'm sure I'm pretty much alone on this one, but I never could stand the Genesis controllers. They felt flimsy and hollow, and the buttons were hard to use. I think it was the fact that the buttons were sunk, or at the same level as the rest of the controller. But I never liked the PS controllers either, and I get flamed on that too. The XBOX controllers are just superior in every way....but that's another thread.

Oh, if I was to rank the systems:
1st Place - Turbo Grafx 16/PC Engine: Just one charming little piece of machinery with a ton of great games. Of course there's the whole "Turbografx is actually just an 8 Bit system" argument, but if that's the case then it just makes the Turbo Grafx even better. What does that say about the Genesis's "blast processing" if the Turbo (just a little 8-bit nobody) can dish out the same thing or better.
2nd Place - Super Nintendo/Super Famicon: A very close second. I love Nintendo. It also has the charm factor with all of its systems. It has great shooters like R Type III (worth getting the SNES just for that game), Rock n' Roll racing, etc... SNES has great scrolling as well and a great controller with 6 buttons.
3rd Place - Genesis: I never could really learn to love this machine, though it did have some great games (such as the above mentioned Streets of Rage, Strider, Ghouls and Ghosts and the ultra cool Disney games.). The Genesis just didn't have that charm factor going on like the SNES and the Turbografx. I found the controllers not necessarily uncomfortable, but just annoying to use...in spite of the fact that it did sport one extra button over the Turbografx controller.
In the end, I would like to have all three systems.

Each system had their own selection of great games making each system great in their own way....man I would love to play Streets of Rage right now....

So Genesis lovers don't hate me for my blasphemy.

I was just giving my two cents.